Search Dictionary



Version history

  • Current: Jun 13, 2024

Primordial germ cell (PGC)

The primordial germ cell (PGC) is a stem cell that differentiates into a spermatozoon or an oocyte.




Definitions in the literature

  • In humans, the primordial germ cell (PGC) is the primary undifferentiated stem cell type that will differentiate towards gametes: spermatozoa or oocytes [1].
  • Primordial germ cells (PGCs) are specialized embryonic cells formed early in development and fated to produce gametes in the adult gonad [2].