WANI Dictionary

Lipogenesis

Lipogenesis refers to the biosynthesis of fats (triacylglycerols, TAGs).

A TAG molecule consists of one glycerol molecule and three fatty acid molecules. Lipogenesis often includes the synthesis of fatty acids from acetyl-CoAs. In vertebrates, lipogenesis mainly takes place in the liver and adipose tissues.

Definitions in the literature

• Lipogenesis is defined as de novo fat synthesis and includes fatty acid synthesis and subsequent conversion of fatty acids to triglycerides in the liver and adipose tissue [1].
• Adipogenesis refers to the cellular process of adipocyte differentiation, whereas lipogenesis is defined as fatty acid and triglyceride (TG) biosynthesis from acetyl-CoA [2].