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- Current: Jan 30, 2025
Inflammation
Inflammation is the physiological condition of tissue characterized by the presence of:
- Swelling
- Elevated temperature
- Redness
- Intensive sensation of a noxious stimulus
- Impaired function
Definitions in the literature
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- At present, inflammation is defined by the presence of five macroscopic pathological phenomena, four of them proposed by Celsus as long as 2000 years ago. These are tumor - swelling of the tissue, calor – elevated tissue temperature, rubor – blood color-like redness of vascularized tissue at the inflammation site, dolor – intensive sensation of a noxious stimulus, and functio laesa, i.e. impaired function of the organ affected [1].