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  • Current: Jan 30, 2025

Inflammation

Inflammation is the physiological condition of tissue characterized by the presence of:

  1. Swelling
  2. Elevated temperature
  3. Redness
  4. Intensive sensation of a noxious stimulus
  5. Impaired function


Definitions in the literature

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  • At present, inflammation is defined by the presence of five macroscopic pathological phenomena, four of them proposed by Celsus as long as 2000 years ago. These are tumor - swelling of the tissue, calor – elevated tissue temperature, rubor – blood color-like redness of vascularized tissue at the inflammation site, dolor – intensive sensation of a noxious stimulus, and functio laesa, i.e. impaired function of the organ affected [1].