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- Current: Jun 20, 2022
Aging
Aging is the time-independent functional and structural changes in organisms that result in the decline of body functions.
In general, aging is caused by the accumulation of molecular-level damages and begins after the reproductive maturation.
Definitions in the literature
- the gradual accumulation of damage to essential biological molecules, particularly DNA in both the nucleus and mitochondria, resulting in defects in cell functioning, declining health, and ultimately death [1].
- As a result of this survey, we may define aging as the time-independent series of cumulative, progressive, intrinsic, and deleterious functional and structural changes that usually begin to manifest themselves at reproductive maturity and eventually culminate in death [2].